COMPOSITION:

Each 100ml contains: Levofloxacin (as hemihydrate)…. 500mg

INDICATIONS:

BEXUS I.V. Infusion is indicated for the treatment of adults with mild, moderate, and severe infections caused by susceptible strains of the designated microorganisms in the conditions listed below, when intravenous administration offers a route of administration advantageous to the patient (e.g., patient cannot tolerate an oral dosage form).

Acute maxillary sinusitis

Due to Streptococcus pneumoniae, Haemophilus influenzae or Moraxella catarrhalis.

Acute bacterial exacerbation of chronic bronchitis

Due to Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae or Moraxella catarrhalis.

Nosocomial pneumonia

Due to methicillin-susceptible Staphylococcus aureus, Pseudomonas aeruginosa, Serratia marcescens, Escherichia coli, Klebsiella pneumoniae, Haemophilus influenzae, or Streptococcus pneumoniae. Adjunctive therapy should be used as clinically indicated. Where Pseudomonas aeruginosa is a documented or presumptive pathogen, combination therapy with an anti-pseudomonal (beta)-lactam is recommended.

Community-acquired pneumonia

Due to Staphylococcus aureus, Streptococcus pneumoniae (including penicillin-resistant strains, MIC value for penicillin >/=2μg/mL), Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella pneumoniae, Moraxella catarrhalis, Chlamydia pneumoniae, Legionella pneumophila or Mycoplasma pneumoniae.

Complicated skin and skin structure infections

Due to methicillin-susceptible Staphylococcus aureus, Enterococcus faecalis, Streptococcus pyogenes or Proteus mirabilis.

Uncomplicated skin and skin structure infections

(Mild to moderate) including abscesses, cellulitis, furuncles, impetigo, pyoderma, wound infections due to Staphylococcus aureus or Streptococcus pyogenes.

Chronic bacterial prostatitis

Due to Escherichia coli, Enterococcus faecalis or Staphylococcus epidermidis.

Complicated urinary tract infections

(Mild to moderate) due to Enterococcus faecalis, Enterobacter cloacae, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis or Pseudomonas aeruginosa.

Acute pyelonephritis

(Mild to moderate) caused by Escherichia coli.

Uncomplicated urinary tract infections

(Mild to moderate) due to Escherichia coli, Klebsiella pneumoniae or Staphylococcus saprophyticus.

Intra-abdominal infections:

In presence of susceptible organism.

PRESENTATION:

Available in 100ml vial